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Selected Publications

  • Dovey J, Zacharek S, Kim CF*, Lees JA*. Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion. Proc. Natl. Acad. Sc. 2008, Aug 19;105(33):11857-62. *co-corresponding authors
  • Yang Y, Iwanaga K, Raso MG, Wislez M, Hanna AE, Wieder ED, Molldrem JJ, Wistuba II, Powis G, Demayo FJ, Kim CF, Kurie JM. Phosphatidylinositol 3-Kinase Mediates Bronchioalveolar Stem Cell Expansion in Mouse Models of Oncogenic K-ras-induced Lung Cancer. PLoS ONE. 2008; in press
  • Nolen-Walston RD*, Kim CF*, Mazan MR, Ingenito EP, Gruntman AM, Tsai L, Boston R, Woolfenden AE, Jacks T, Hoffman AM. Cellular kinetics and modeling of bronchioalveolar stem cell response during lung regeneration. American Journal of Physiology: Lung Cellular and Molecular Physiology. 2008. Jun;294(6):L1158-65.; *equal contribution as first author
  • Perera SA, Maser RS, Xia H, McNamara K, Protopopov A, Chen L, Hezel A, Kim CF, Bronson RT, Castrillon DH, Chin L, Bardeesy N, Depinho RA, Wong KK. Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer. Carcinogenesis. 2008 Feb 17; [Epub ahead of print].
  • Kim CF. Paving the road for lung stem cell biology: bronchioalveolar stem cells and other putative distal lung stem cells. Am J Physiol Lung Cell Mol Physiol. 2007; 296:L1092-8.
  • Kissil JL, Walmsley MJ, Hanlon L, Haigis K, Kim CFB, Sweet-Cordero A, Eckman MS, Tuveson DA, Capobianco AJ, Tybulewicz VLJ, Jacks T. Requirement for Rac1 in a K-ras–Induced Lung Cancer in the Mouse. Cancer Research 2007; 67:8089-8094.
  • Sicinski P, Zacharek S, Kim, C. Duality of p27 funciton in tumorigenesis. Genes and Development 2007;21: 1703-1706.
  • Kim, CFB. MAPK-ing out the pathways in lung stem cell regulation. Cell Stem Cell 2007; 1:11-13.
  • Danielian PS, Kim CFB, Caron AM, Vasile E, Bronson RT, Lees JA. E2f4 is required for the normal development of proximal respiratory epithelium. Developmental Biology 2007;305:564-576.
  • Kim, CFB. Advancing the field of lung stem cell biology. Frontiers in Bioscience 2007;12:3117-3124.
  • Kim, CFB, Jackson EL, Kirsch DG, Grimm J, Shaw AT, Lane K, Kissil J, Olive KP, Sweet-Cordero A, Weissleder, Jacks T. Mouse models of human non-small-cell lung cancer: raising the bar. Cold Spring Harbor Symposia on Quantitative Biology, 2005, Volume LXX:241-250.
  • H J, Houghton AM, Mariani TJ, Perera S, Kim CB, Padera R, Tonon G, McNamara K, Marconcini LA, Hezel A, El-Bardeesy N, Bronson RT, Sugarbaker D, Maser RS, Shapiro SD, Wong KK. K-ras activation generates an inflammatory response in lung tumors. Oncogene 2006;25:2105-12.
  • Morales M, Theunissen J-W, Kim CFB, Kitagawa R, Kastan MB, Petrini JHJ. The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor. Genes and Development 2005;19:3043-3054.
  • Grimm J, Kirsch DG, Windsor SD, Kim CFB, Santiago PM, Ntziachristos V, Jacks T, Weissleder R. Use of gene expression profiling to direct in vivo molecular imaging of lung cancer. Proc. Natl. Acad. Sc. 2005;102:14404-14409.
  • Kim CFB, Jackson EL, Woolfenden AE, Lawrence S, Babar I, Vogel S, Crowley D, Bronson RT, Jacks T. Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 2005;121:823-35.
  • Bender CF, Sikes ML, Sullivan R, Huye LE, Le Beau MM, Roth DB, Oltz EM, Petrini JHJ. Cancer predisposition and hematopoietic failure in Rad50S/S mice. Genes and Development, 2002; 16:2237-2251.
  • Luo G, Yao MS, Bender CF, Mills M, Bladl AR, Bradley A, Petrini JHJ. Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation. Proc. Natl. Acad. Sc. 1999; 96:7376-7381.